We believe a cure or treatment should exist for every disease and every person.

Who we are

Neuro Pioneers on a Quest to Cure

At QurAlis, we consider ourselves “neuro pioneers” because we are driven to explore the deepest aspects of human neurology in order to find the treatments patients urgently need. We work with a relentless pursuit of knowledge, a precise attention to craft, and an optimistic mindset to discover and develop effective precision medicines that have the potential to alter the trajectory of ALS, FTD, and other neurodegenerative and neurological diseases.

We dedicated ourselves to this challenge with the foundational belief that a cure or treatment should exist for every disease and every person.

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Cracking the Code: The Critical Role of TDP-43

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease impacting nerve cells in the brain and spinal cord, reducing muscle function and control.

The QurAlis team together with others in the field cracked the code on sporadic ALS through the identification of major disease drivers linked to TDP-43 pathology.

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Breaking Through

QurAlis is breaking through the barriers of science in our quest to bring much-needed precision therapies to patients.

QurAlis is currently advancing a pipeline with therapeutic candidates that target specific components of ALS pathology and defined ALS patient populations based on both disease-causing genetic mutation(s) and clinical biomarkers.

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Our Platforms

FlexASO™: Proprietary Anti-Sense Oligonucleotide Splice Modulator Platform

Bespoke platform key to tackling the spectrum of neurodegenerative and neurological diseases.

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QR43™: Proprietary & Investigative TDP-43 Platform

Investigative platform dedicated to discovering and developing precision therapies for TDP-43-related diseases

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